论文标题
建模呼吸液滴的环境温度和相对湿度敏感性及其在Covid-19爆发中的作用
Modeling ambient temperature and relative humidity sensitivity of respiratory droplets and their role in Covid-19 outbreaks
论文作者
论文摘要
围绕COVID-19大流行的许多未解决的问题之一是局部暴发是否取决于温度和相对湿度等环境条件。在本文中,我们开发了一个模型,该模型试图解释和描述呼吸液滴的温度和相对湿度敏感性及其在确定病毒爆发方面的可能联系。该模型有两个部分。首先,我们根据反应机制对感染人群的生长速率进行建模 - 其最终方程与众所周知的SIR模型相似。使用反应机制对大流行进行建模的优点是速率常数具有健全的物理解释。感染速率常数是使用碰撞率理论得出的,并被证明是呼吸液滴寿命的函数。在第二部分中,我们模仿了负责疾病传播的呼吸液滴作为盐溶液液滴,并计算出其蒸发时间,以核算液滴冷却,热量和传质,并最终结晶盐。该模型输出与实验获得的纯水和盐溶液的悬浮液滴的蒸发特性相比,从而确保了模型的保真度。在室外和室内条件下,液滴蒸发/干燥时间确实取决于环境温度和相对湿度。由于液滴蒸发时间决定了感染率常数,因此显示环境温度和相对湿度会影响爆发的生长速率。
One of the many unresolved questions that revolves around the Covid-19 pandemic is whether local outbreaks can depend on ambient conditions like temperature and relative humidity. In this paper, we develop a model that tries to explain and describe the temperature and relative humidity sensitivity of respiratory droplets and their possible connection in determining viral outbreaks. The model has two parts. First, we model the growth rate of the infected population based on a reaction mechanism - the final equations of which are similar to the well-known SIR model. The advantage of modeling the pandemic using the reaction mechanism is that the rate constants have sound physical interpretation. The infection rate constant is derived using collision rate theory and shown to be a function of the respiratory droplet lifetime. In the second part, we have emulated the respiratory droplets responsible for disease transmission as salt solution droplets and computed their evaporation time accounting for droplet cooling, heat and mass transfer and finally crystallization of the salt. The model output favourably compares with the experimentally obtained evaporation characteristics of levitated droplets of pure water and salt solution, respectively, ensuring fidelity of the model. Droplet evaporation/desiccation time is indeed dependent on ambient temperature and relative humidity, considered at both outdoor and indoor conditions. Since the droplet evaporation time determines the infection rate constant, ambient temperature and relative humidity are shown to impact the outbreak growth rates.