论文标题
电子光束电流变压器的低噪声优化用于传统放射疗法，直至超高剂量辐射
Low noise optimization of an electron beam current transformer for conventional radiotherapy up to ultra high dose rate irradiations
论文作者
论文摘要
超高剂量速率电子束也称为闪光灯放射疗法，在几项河止癌症治疗研究中变得越来越重要。但是，由于辐照过程中使用的剂量率，迄今为止尚无实时剂量监测装置。在这项工作中，我们介绍了梁电流变压器（BCT）的开发，从铁磁成分的选择以及屏蔽的实现到基于反式阻抗电路的前端电子设备的设计，以便对检测器进行低噪声优化。 BCT原型能够监视光束电流范围从1.2〜 \ textmu a到200〜Ma，其上升时间常数高于20〜NS，并且信号的下垂速率低于0.05 \％$ \ cdot $ \ cdot $ \ textmu s $ s $ s $^{ - 1} $。还提出了初步的原位测量。目的是将实时测量光束电流测量的BCT系统组合到电离室，以监测光束形状和位置，以提供可靠的剂量监测系统。
Ultra high dose rate electron beams also known as FLASH radiotherapy is becoming of importance in several preclinial cancer treatment studies. However, due to the dose rate used during the irradiation sessions, no real time dose monitoring device exists to date. In this work, we present the development of a beam current transformer (BCT), from the choice of the ferromagnetic component and the realisation of the shielding to the design of a front-end electronics based on a trans-impedance circuit in order to perform a low noise optimization of the detector. The BCT prototype is able to monitor a beam current range from 1.2~\textmu A to 200~mA with a rise time constant better than 20~ns and a droop rate of the signal below 0.05\%$\cdot$\textmu s$^{-1}$. Preliminary in-situ measurements are also presented. The goal is to combine the BCT system which measure in real time the beam current, to an ionisation chamber monitoring the beam shape and position in order to provide a reliable dose monitoring system.
