论文标题
从2D移至3D：直肠癌分期的体积医学图像分类
Moving from 2D to 3D: volumetric medical image classification for rectal cancer staging
论文作者
论文摘要
来自磁共振成像（MRI）的体积图像在直肠癌的术前分期提供了宝贵的信息。最重要的是，T2和T3阶段之间的准确术前歧视可以说是直肠癌治疗的最具挑战性和临床意义的任务，因为通常建议对T3（或更大）阶段癌症患者进行化学疗法。在这项研究中，我们提出了一个体积卷积神经网络，可准确区分T2与直肠MR体积的T3阶段直肠癌。具体而言，我们建议1）一种基于自定义的基于重新连接的音量编码器，该编码器与晚期融合（即最后一层的3D卷积）建模，2）双线性计算，该计算将编码器产生的特征汇总为创建体积智能特征，而3）最小化三胞胎损失和局灶性损失的关节。通过病理确认的T2/T3直肠癌的MR量，我们进行了广泛的实验，以比较残留学习框架内的各种设计。结果，我们的网络达到了0.831的AUC，高于专业放射科医生组的准确性。我们认为该方法可以扩展到其他卷分析任务
Volumetric images from Magnetic Resonance Imaging (MRI) provide invaluable information in preoperative staging of rectal cancer. Above all, accurate preoperative discrimination between T2 and T3 stages is arguably both the most challenging and clinically significant task for rectal cancer treatment, as chemo-radiotherapy is usually recommended to patients with T3 (or greater) stage cancer. In this study, we present a volumetric convolutional neural network to accurately discriminate T2 from T3 stage rectal cancer with rectal MR volumes. Specifically, we propose 1) a custom ResNet-based volume encoder that models the inter-slice relationship with late fusion (i.e., 3D convolution at the last layer), 2) a bilinear computation that aggregates the resulting features from the encoder to create a volume-wise feature, and 3) a joint minimization of triplet loss and focal loss. With MR volumes of pathologically confirmed T2/T3 rectal cancer, we perform extensive experiments to compare various designs within the framework of residual learning. As a result, our network achieves an AUC of 0.831, which is higher than the reported accuracy of the professional radiologist groups. We believe this method can be extended to other volume analysis tasks
